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In 2025, Sydney tech entrepreneur Paul Conyngham used ChatGPT and AI tools to help design a personalised mRNA cancer vaccine for his rescue dog Rosie, a staffy–Shar Pei cross diagnosed with mast cell cancer.
- After conventional chemotherapy slowed but failed to shrink the tumours, Conyngham used AI to help sequence Rosie's tumour DNA, identify mutations, and design an mRNA vaccine.
- The vaccine was manufactured at the UNSW RNA Institute and administered under ethics approval at the University of Queensland.
- Rosie received her first injection in December 2025, followed by a booster in early 2026.
- Results became visible about a month after treatment, with the primary tumour shrinking by approximately 75%, though at least one tumour did not respond.
- This resolves based on my subjective judgment of whether the result appears to be a legitimate, real therapeutic effect — not a fluke, misattribution, or hype cycle.
